Macrozide 500 Tablet
strip of 6.0 tablets.Prescription required
About this product:
| Salt Composition: | Pyrazinamide (500mg) |
| Manufacturer: | Macleods Pharmaceuticals Pvt Ltd |
| Storage: | Below 25 degree celcius |
Out of Stock
Have doubts about this medicine?
Have doubts about this medicine?
Macrozide 500 Tablet is an antibiotic that belongs to a class of medicines known as anti-tuberculosis drugs. It is used in the treatment of tuberculosis, an infectious disease that mainly affects the lungs and in some cases other parts of the body. Macrozide 500 Tablet is given in combination with at least one other tuberculosis medicine. It acts by killing the causative bacteria. It should be used in the dose and duration as advised by your doctor. This medicine may be taken with or without food, preferably at a fixed time every day to avoid a missed dose. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and increase the side effects too. Please let your doctor know about any changes in your weight as the dose of this medicine depends on the overall body weight of a person. Any changes in weight might need dose modification.
Macrozide 500 Tablet is an antitubercular medicine. In the body, it gets converted to pyrazinoic acid. This pyrazinoic acid inhibits fatty acid synthase I (bacterial enzyme) which is essential for bacterial growth. Thus, it works as a bacteriocidal to prohibit their growth and treats tuberculosis.
What is Macrozide 500 Tablet and what is it used for?
Macrozide 500 Tablet is an antibiotic. It is used in combination with other antibiotics to treat tuberculosis.
Is Macrozide 500 Tablet bactericidal?
Macrozide 500 Tablet is both bacteriostatic and bactericidal. It inhibits the growth of bacteria (bacteriostatic) in certain cases and kills (bactericidal) tuberculosis-causing bacteria in other cases.
How does Macrozide 500 Tablet work/treat tuberculosis?
Macrozide 500 Tablet kills or stops the growth of bacteria that cause tuberculosis (Mycobacterium tuberculosis). The exact mechanism of action for Macrozide 500 Tablet is not known.
How does Macrozide 500 Tablet cause hyperuricemia and gout?
Macrozide 500 Tablet undergoes metabolism in the body to become pyrazinoic acid (active chemical form of Macrozide 500 Tablet). This pyrazinoic acid then inhibits the excretion of urates (salt form of uric acid) by the kidneys. This leads to an increase in blood levels of uric acid, known as hyperuricemia. Excess uric acid accumulation between joints can cause pain, swelling, redness, and stiffness in joints (gout).
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Macrozide 500 Tablet may be taken with or without food, but it is better to take it at a fixed time.
- Do not forget a dose as this increases the risk of the bacteria becoming resistant to the medicine and also increases the risk of getting side effects.
- Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
- Avoid drinking alcohol while taking Macrozide 500 Tablet as this may increase the risk of side effects on the liver.
- Use a reliable contraceptive method (such as condoms or a diaphragm) to prevent pregnancy while you are taking Macrozide 500 Tablet as it may make hormonal contraceptives such as the pill less effective.
- No common side effects listed.
Alcohol
Caution is advised when consuming alcohol with Macrozide 500 Tablet. Please consult your doctor.
Breastfeed
Macrozide 500 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Pregnancy
Macrozide 500 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.