Glygon M 80mg/500mg Tablet

What is Glygon M 80mg/500mg Tablet?

Glygon M 80mg/500mg Tablet is a combination medication comprising Gliclazide and Metformin. It is primarily used in the treatment of type 2 diabetes mellitus (DM). This medication works by improving blood glucose levels in adults when taken alongside a proper diet and regular exercise. Gliclazide lowers blood glucose levels by stimulating insulin release from the pancreas, while Metformin reduces glucose production in the liver and enhances insulin sensitivity. Importantly, this combination is not indicated for treating Type 1 DM.

What are the possible side effects of Glygon M 80mg/500mg Tablet?

The use of Glygon M 80mg/500mg Tablet may be associated with common side effects, including hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory tract infection. Additionally, its use can lead to serious but rare side effects like lactic acidosis. Furthermore, long-term use of this medication can result in vitamin B12 deficiency.

Can the use of Glygon M 80mg/500mg Tablet cause hypoglycemia?

Yes, the use of Glygon M 80mg/500mg Tablet can lead to hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. This condition is more likely to occur if you miss or delay your food, consume alcohol, over-exercise, or take other antidiabetic medications alongside it. Therefore, regular monitoring of blood sugar levels is crucial, and keeping glucose tablets, honey, or fruit juice handy is recommended.

Can the use of Glygon M 80mg/500mg Tablet cause lactic acidosis?

Yes, the use of Glygon M 80mg/500mg Tablet can lead to lactic acidosis. This is a medical emergency caused by increased levels of lactic acid in the blood, also known as Metformin-associated Lactic Acidosis (MALA). It is a rare side effect associated with the use of metformin. This condition is avoided in patients with underlying kidney disease, old age patients, or those who consume large amounts of alcohol. Symptoms of lactic acidosis include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty breathing, nausea, vomiting, stomach pain, or slow heart rate. If you experience these symptoms, stop taking Glygon M 80mg/500mg Tablet immediately and consult your doctor.

Can the use of Glygon M 80mg/500mg Tablet lead to Vitamin B12 deficiency?

Yes, the use of Glygon M 80mg/500mg Tablet can cause vitamin B12 deficiency on long-term use. This deficiency occurs as the medication interferes with the absorption of vitamin B12 in the stomach. If left untreated, it may cause anemia and nerve problems, resulting in a tingling sensation and numbness in hands and feet, weakness, urinary problems, changes in mental status, and difficulty maintaining balance (ataxia). To prevent such problems, researchers suggest taking vitamin B12 from outside sources at least once every year.

Are there any specific conditions in which Glygon M 80mg/500mg Tablet should not be taken?

The use of Glygon M 80mg/500mg Tablet should be avoided in patients with known allergies to any components or excipients of this medication. Additionally, it is contraindicated in patients with moderate to severe kidney disease or underlying metabolic acidosis, including diabetic ketoacidosis.

Is it safe to take alcohol while I am also taking Glygon M 80mg/500mg Tablet?

No, it is not safe to consume alcohol alongside Glygon M 80mg/500mg Tablet. This can lower your blood sugar levels (hypoglycemia) and increase the chances of lactic acidosis.