


| Salt Composition: | Methotrexate (2.5mg) |
| Manufacturer: | Zydus Cadila |
| Storage: | Below 25 degree celcius |
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Have doubts about this medicine?
Have doubts about this medicine?
Mexate 2.5 Tablet is a medicine used for treatment of cancer in various parts of the body, rheumatoid arthritis, severe and uncontrolled psoriasis, and Crohn's disease. Mexate 2.5 Tablet may be used alone or in combination with other medicines. You should take it exactly as your doctor has advised. Taking too much of it can cause serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid consumption of alcohol while taking this medicine as it may increase your risk of liver damage. The most common side effects of this medicine are ulcerative stomatitis, hair loss, low blood cell count, increased liver enzymes, nausea, and abdominal distress.
Mexate 2.5 Tablet inhibits enzymes (dihydrofolate reductase), prevents cell division and leads to anti-inflammatory actions. Mexate 2.5 Tablet kills cancer cells by preventing them from making DNA. Mexate 2.5 Tablet can help control psoriasis by retarding the production of skin cells and suppressing inflammation. Mexate 2.5 Tablet may treat rheumatoid arthritis by suppressing the immune system, preventing it from attacking the body's cells. This helps reduce the inflammation that causes swollen and stiff joints in rheumatoid arthritis or damage to bowel in Crohn's disease.
Can Mexate 2.5 Tablet cause mouth ulcers?
Yes, mouth ulcers and sore mouth are potential side effects of Mexate 2.5 Tablet in some cases. Taking folic acid may help alleviate these symptoms. Your doctor can advise on reducing the dosage to further minimize this issue.
Why is it necessary to take folic acid with Mexate 2.5 Tablet?
Folic acid is required for cell production in the body, and Mexate 2.5 Tablet decreases folic acid levels. Folic acid can help reduce common side effects like mouth ulcers, hair loss, nausea, heartburn, abdominal pain, fatigue, anemia, and liver problems.
Why are regular blood tests required while taking Mexate 2.5 Tablet?
Regular blood tests will allow your doctor to monitor your response to Mexate 2.5 Tablet and detect any side effects early on. This includes checking liver function and blood counts (white blood cells, red blood cells, and platelets). Additional tests may be ordered based on the results.
Can taking Mexate 2.5 Tablet increase my risk of infections?
Yes, Mexate 2.5 Tablet can decrease immune system activity, potentially leading to serious infections. Rare cases have been reported where lung infections occurred while using this medication. If you have an active infection, use Mexate 2.5 Tablet with caution.
Can Mexate 2.5 Tablet affect fertility?
Yes, it may decrease sperm count in males and cause menstrual disturbances in females. These effects are reversible and will cease once the treatment is discontinued.
What should I do if I am planning to become pregnant and my husband is taking Mexate 2.5 Tablet?
Avoid pregnancy while your husband takes Mexate 2.5 Tablet, and also avoid conception for at least three months after the therapy as it may lead to serious fetal abnormalities.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush, or break it. Mexate 2.5 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Alcohol
It is unsafe to consume alcohol with Mexate 2.5 Tablet.
Breastfeed
Mexate 2.5 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Pregnancy
Mexate 2.5 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.