Dianorm-M Tablet

What is Dianorm-M Tablet?

Dianorm-M Tablet is a combination medication containing Gliclazide and Metformin, used to treat type 2 diabetes mellitus (DM) in adults. It improves blood glucose levels when taken with a proper diet and regular exercise. Gliclazide works by increasing insulin release from the pancreas, while Metformin lowers glucose production in the liver and improves insulin sensitivity.

What are the possible side effects of Dianorm-M Tablet?

Common side effects include hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory tract infection. Rare but serious side effects like lactic acidosis can occur, particularly in patients with underlying kidney disease or those who consume large amounts of alcohol. Long-term use may also lead to vitamin B12 deficiency.

Can the use of Dianorm-M Tablet cause hypoglycemia?

Yes, Dianorm-M Tablet can cause low blood sugar levels (hypoglycemia). Symptoms include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. Regular monitoring of blood sugar levels is essential, and having glucose tablets, honey, or fruit juice nearby can help manage hypoglycemic episodes.

Can the use of Dianorm-M Tablet cause lactic acidosis?

Yes, Dianorm-M Tablet can lead to lactic acidosis, a medical emergency characterized by increased levels of lactic acid in the blood. This rare side effect is associated with Metformin use and is avoided in patients with underlying kidney disease, old age, or those who consume large amounts of alcohol. Symptoms include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty breathing, nausea, vomiting, stomach pain, or slow heart rate.

Can the use of Dianorm-M Tablet lead to Vitamin B12 deficiency?

Yes, long-term use of Dianorm-M Tablet can cause vitamin B12 deficiency. This occurs as the medication interferes with vitamin B12 absorption in the stomach. If left untreated, it may lead to anemia and nerve problems, resulting in symptoms such as tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status, and difficulty maintaining balance (ataxia). Some researchers suggest taking vitamin B12 supplements from outside sources at least once a year to avoid these issues.

Are there any specific conditions in which Dianorm-M Tablet should not be taken?

Dianorm-M Tablet should be avoided in patients with known allergies to the medication's components or excipients. It is also contraindicated in patients with moderate to severe kidney disease or underlying metabolic acidosis, including diabetic ketoacidosis.

Is it safe to take alcohol while taking Dianorm-M Tablet?

No, consuming alcohol while on Dianorm-M Tablet is not safe. It can lower blood sugar levels (hypoglycemia) and increase the chances of lactic acidosis.